We present the new CTEQ-TEA global analysis of quantum chromodynamics (QCD). In this analysis, parton distribution functions (PDFs) of the nucleon are determined within the Hessian method at the next-to-next-to-leading order (NNLO) in perturbative QCD, based on the most recent measurements from the Large Hadron Collider (LHC) and a variety of world collider data. Because of difficulties in fitting both the ATLAS 7 and 8 TeV $W$ and $Z$ vector boson production cross section data, we present four families of (N)NLO CTEQ-TEA PDFs, named CT18, A, X and Z PDFs, respectively. We study the impact of the CT18 family of PDFs on the theoretical predictions of standard candle cross sections at the LHC.