We summarize some of the compelling new scientific opportunities for understanding stars and stellar systems that can be enabled by sub-milliarcsec (sub-mas) angular resolution, UV-Optical spectral imaging observations, which can reveal the details of the many dynamic processes (e.g., evolving magnetic fields, accretion, convection, shocks, pulsations, winds, and jets) that affect stellar formation, structure, and evolution. These observations can only be provided by long-baseline interferometers or sparse aperture telescopes in space, since the aperture diameters required are in excess of 500 m (a regime in which monolithic or segmented designs are not and will not be feasible) and since they require observations at wavelengths (UV) not accessible from the ground. Such observational capabilities would enable tremendous gains in our understanding of the individual stars and stellar systems that are the building blocks of our Universe and which serve as the hosts for life throughout the Cosmos.