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Register a new userINN: Inflated Neural Networks for IPMN Diagnosis
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Added by
Rodney LaLonde Iii
Publication date
2019
fields
Informatics Engineering
and research's language is
English
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Intraductal papillary mucinous neoplasm (IPMN) is a precursor to pancreatic ductal adenocarcinoma. While over half of patients are diagnosed with pancreatic cancer at a distant stage, patients who are diagnosed early enjoy a much higher 5-year survival rate of $34%$ compared to $3%$ in the former; hence, early diagnosis is key. Unique challenges in the medical imaging domain such as extremely limited annotated data sets and typically large 3D volumetric data have made it difficult for deep learning to secure a strong foothold. In this work, we construct two novel inflated deep network architectures, $textit{InceptINN}$ and $textit{DenseINN}$, for the task of diagnosing IPMN from multisequence (T1 and T2) MRI. These networks inflate their 2D layers to 3D and bootstrap weights from their 2D counterparts (Inceptionv3 and DenseNet121 respectively) trained on ImageNet to the new 3D kernels. We also extend the inflation process by further expanding the pre-trained kernels to handle any number of input modalities and different fusion strategies. This is one of the first studies to train an end-to-end deep network on multisequence MRI for IPMN diagnosis, and shows that our proposed novel inflated network architectures are able to handle the extremely limited training data (139 MRI scans), while providing an absolute improvement of $8.76%$ in accuracy for diagnosing IPMN over the current state-of-the-art. Code is publicly available at https://github.com/lalonderodney/INN-Inflated-Neural-Nets.
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Neural architecture search (NAS) has witnessed prevailing success in image classification and (very recently) segmentation tasks. In this paper, we present the first preliminary study on introducing the NAS algorithm to generative adversarial networks (GANs), dubbed AutoGAN. The marriage of NAS and GANs faces its unique challenges. We define the search space for the generator architectural variations and use an RNN controller to guide the search, with parameter sharing and dynamic-resetting to accelerate the process. Inception score is adopted as the reward, and a multi-level search strategy is introduced to perform NAS in a progressive way. Experiments validate the effectiveness of AutoGAN on the task of unconditional image generation. Specifically, our discovered architectures achieve highly competitive performance compared to current state-of-the-art hand-crafted GANs, e.g., setting new state-of-the-art FID scores of 12.42 on CIFAR-10, and 31.01 on STL-10, respectively. We also conclude with a discussion of the current limitations and future potential of AutoGAN. The code is available at https://github.com/TAMU-VITA/AutoGAN
Mathematical morphology is a theory and technique to collect features like geometric and topological structures in digital images. Given a target image, determining suitable morphological operations and structuring elements is a cumbersome and time-consuming task. In this paper, a morphological neural network is proposed to address this problem. Serving as a nonlinear feature extracting layer in deep learning frameworks, the efficiency of the proposed morphological layer is confirmed analytically and empirically. With a known target, a single-filter morphological layer learns the structuring element correctly, and an adaptive layer can automatically select appropriate morphological operations. For practical applications, the proposed morphological neural networks are tested on several classification datasets related to shape or geometric image features, and the experimental results have confirmed the high computational efficiency and high accuracy.
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Convolutional neural networks (CNNs) have achieved state-of-the-art results on many visual recognition tasks. However, current CNN models still exhibit a poor ability to be invariant to spatial transformations of images. Intuitively, with sufficient layers and parameters, hierarchical combinations of convolution (matrix multiplication and non-linear activation) and pooling operations should be able to learn a robust mapping from transformed input images to transform-invariant representations. In this paper, we propose randomly transforming (rotation, scale, and translation) feature maps of CNNs during the training stage. This prevents complex dependencies of specific rotation, scale, and translation levels of training images in CNN models. Rather, each convolutional kernel learns to detect a feature that is generally helpful for producing the transform-invariant answer given the combinatorially large variety of transform levels of its input feature maps. In this way, we do not require any extra training supervision or modification to the optimization process and training images. We show that random transformation provides significant improvements of CNNs on many benchmark tasks, including small-scale image recognition, large-scale image recognition, and image retrieval. The code is available at https://github.com/jasonustc/caffe-multigpu/tree/TICNN.
Wrist Fracture is the most common type of fracture with a high incidence rate. Conventional radiography (i.e. X-ray imaging) is used for wrist fracture detection routinely, but occasionally fracture delineation poses issues and an additional confirmation by computed tomography (CT) is needed for diagnosis. Recent advances in the field of Deep Learning (DL), a subfield of Artificial Intelligence (AI), have shown that wrist fracture detection can be automated using Convolutional Neural Networks. However, previous studies did not pay close attention to the difficult cases which can only be confirmed via CT imaging. In this study, we have developed and analyzed a state-of-the-art DL-based pipeline for wrist (distal radius) fracture detection -- DeepWrist, and evaluated it against one general population test set, and one challenging test set comprising only cases requiring confirmation by CT. Our results reveal that a typical state-of-the-art approach, such as DeepWrist, while having a near-perfect performance on the general independent test set, has a substantially lower performance on the challenging test set -- average precision of 0.99 (0.99-0.99) vs 0.64 (0.46-0.83), respectively. Similarly, the area under the ROC curve was of 0.99 (0.98-0.99) vs 0.84 (0.72-0.93), respectively. Our findings highlight the importance of a meticulous analysis of DL-based models before clinical use, and unearth the need for more challenging settings for testing medical AI systems.
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