We consider a Gaussian multiple-access channel where the number of transmitters grows with the blocklength $n$. For this setup, the maximum number of bits that can be transmitted reliably per unit-energy is analyzed. We show that if the number of users is of an order strictly above $n/log n$, then the users cannot achieve any positive rate per unit-energy. In contrast, if the number of users is of order strictly below $n/log n$, then each user can achieve the single-user capacity per unit-energy $(log e)/N_0$ (where $N_0/ 2$ is the noise power) by using an orthogonal access scheme such as time division multiple access. We further demonstrate that orthogonal codebooks, which achieve the capacity per unit-energy when the number of users is bounded, can be strictly suboptimal.