The origin of dark matter is a driving question of modern physics. Low-energy antideuterons provide a smoking gun signature of dark matter annihilation or decay, essentially free of astrophysical background. Low-energy antiprotons are a vital partner for this analysis, and low-energy antihelium could provide further discovery space for new physics. In the coming decade, AMS-02 will continue accumulating the large statistics and systematic understanding necessary for it to probe rare antinuclei signatures, and GAPS, which is the first experiment optimized specifically for low-energy cosmic antinuclei, will begin several Antarctic balloon campaigns. The connection of cosmic-ray antinuclei and dark matter is reviewed and the outlook in light of experimental progress is presented.
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