In this conference-proceedings contribution, we review recent advances in placing model-independent constraints on the properties of cold and dense QCD matter inside neutron stars. In addition to introducing new bounds for the Equation of State, we explain how these results may be used to make robust statements about the physical phase of strongly interacting matter in the centers of neutron stars of different masses. Our findings indicate that the existence of quark-matter cores inside massive neutron stars appears to be a very common feature of the allowed Equations of State, and should not be considered an exotic or unlikely scenario.