A measurement of the ratio of branching fractions of the decays $B^+to K^+mu^+mu^-$ and $B^+to K^+e^+e^-$ is presented. The proton-proton collision data used correspond to an integrated luminosity of $5.0,$fb$^{-1}$ recorded with the LHCb experiment at centre-of-mass energies of $7$, $8$ and $13,$TeV. For the dilepton mass-squared range $1.1 < q^2 < 6.0,$GeV$^2!/c^4$ the ratio of branching fractions is measured to be $R_K = {0.846,^{+,0.060}_{-,0.054},^{+,0.016}_{-,0.014}}$, where the first uncertainty is statistical and the second systematic. This is the most precise measurement of $R_K$ to date and is compatible with the Standard Model at the level of 2.5 standard deviations.