The epoch of reionization, when photons from early galaxies ionized the intergalactic medium about a billion years after the Big Bang, is the last major phase transition in the Universes history. Measuring the characteristics of the transition is important for understanding early galaxies and the cosmic web and for modeling dwarf galaxies in the later Universe. But such measurements require probes of the intergalactic medium itself. Here we describe how the 21-cm line of neutral hydrogen provides a powerful probe of the reionization process and therefore important constraints on both the galaxies and intergalactic absorbers at that time. While existing experiments will make precise statistical measurements over the next decade, we argue that improved 21-cm analysis techniques - allowing imaging of the neutral gas itself - as well as improved theoretical models, are crucial for testing our understanding of this important era.
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