We present ALMA CO(2-1) observations toward a massive infrared dark cloud G28.37+0.07. The ALMA data reveal numerous molecular (CO) outflows with a wide range of sizes throughout the cloud. Sixty-two 1.3 mm continuum cores were identified to be driving molecular outflows. We have determined the position angle in the plane-of-sky of 120 CO outflow lobes and studied their distribution. We find that the distribution of the plane-of-sky outflow position angles peaks at about 100 degree, corresponding to a concentration of outflows with an approximately east-west direction. For most outflows, we have been able to estimate the plane-of-sky angle between the outflow axis and the filament that harbors the protostar that powers the outflow. Statistical tests strongly indicate that the distribution of outflow-filament orientations is consistent with most outflow axes being mostly orthogonal to their parent filament in 3D. Such alignment may result from filament fragmentation or continuous mass transportation from filament to the embedded protostellar core. The latter is suggested by recent numerical studies with moderately strong magnetic fields.