Explainability and effectiveness are two key aspects for building recommender systems. Prior efforts mostly focus on incorporating side information to achieve better recommendation performance. However, these methods have some weaknesses: (1) prediction of neural network-based embedding methods are hard to explain and debug; (2) symbolic, graph-based approaches (e.g., meta path-based models) require manual efforts and domain knowledge to define patterns and rules, and ignore the item association types (e.g. substitutable and complementary). In this paper, we propose a novel joint learning framework to integrate textit{induction of explainable rules from knowledge graph} with textit{construction of a rule-guided neural recommendation model}. The framework encourages two modules to complement each other in generating effective and explainable recommendation: 1) inductive rules, mined from item-centric knowledge graphs, summarize common multi-hop relational patterns for inferring different item associations and provide human-readable explanation for model prediction; 2) recommendation module can be augmented by induced rules and thus have better generalization ability dealing with the cold-start issue. Extensive experimentsfootnote{Code and data can be found at: url{https://github.com/THUIR/RuleRec}} show that our proposed method has achieved significant improvements in item recommendation over baselines on real-world datasets. Our model demonstrates robust performance over noisy item knowledge graphs, generated by linking item names to related entities.