We present observations of fifty square degrees of the Mopra carbon monoxide (CO) survey of the Southern Galactic Plane, covering Galactic longitudes $l = 300$-$350^circ$ and latitudes $|b| le 0.5^circ$. These data have been taken at 0.6 arcminute spatial resolution and 0.1 km/s spectral resolution, providing an unprecedented view of the molecular clouds and gas of the Southern Galactic Plane in the 109-115 GHz $J = 1$-0 transitions of $^{12}$CO, $^{13}$CO, C$^{18}$O and C$^{17}$O. We present a series of velocity-integrated maps, spectra and position-velocity plots that illustrate Galactic arm structures and trace masses on the order of $sim$10$^{6}$ M$_{odot}$ per square degree; and include a preliminary catalogue of C$^{18}$O clumps located between $l=330$-$340^circ$. Together with information about the noise statistics of the survey these data can be retrieved from the Mopra CO website, the PASA data store and the Harvard Dataverse (doi:10.7910/DVN/LH3BDN ).
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