Using integral field spectroscopic data of 24 nearby spiral galaxies obtained with the Multi-Unit Spectroscopic Explorer (MUSE), we derive empirical calibrations to determine the metallicity of the diffuse ionized gas (DIG) and/or of the low-ionisation emission region (LI(N)ER) in passive regions of galaxies. To do so, we identify a large number of HII--DIG/LIER pairs that are close enough to be chemically homogeneous and we measure the metallicity difference of each DIG/LIER region relative to its HII region companion when applying the same strong line calibrations. The O3N2 diagnostic ($=$log [([O III]/H$beta$)/([N II]/H$alpha$)]) shows a minimal offset (0.01--0.04 dex) between DIG/LIER and HII regions and little dispersion of the metallicity differences (0.05 dex), suggesting that the O3N2 metallicity calibration for HII regions can be applied to DIG/LIER regions and that, when used on poorly resolved galaxies, this diagnostic provides reliable results by suffering little from DIG contamination. We also derive second-order corrections which further reduce the scatter (0.03--0.04 dex) in the differential metallicity of HII-DIG/LIER pairs. Similarly, we explore other metallicity diagnostics such as O3S2 ($=$log([O III]/H$beta$+[S II]/H$alpha$)) and N2S2H$alpha$ ($=$ log([N II]/[S II]) + 0.264log([N II]/H$alpha$)) and provide corrections for O3S2 to measure the metallicity of DIG/LIER regions. We propose that the corrected O3N2 and O3S2 diagnostics are used to measure the gas-phase metallicity in quiescent galaxies or in quiescent regions of star-forming galaxies.
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