We present precision 4.5 $mu$m Spitzer transit photometry of eight planet candidates discovered by the K2 mission: K2-52 b, K2-53 b, EPIC 205084841.01, K2-289 b, K2-174 b, K2-87 b, K2-90 b, and K2-124 b. The sample includes four sub-Neptunes and two sub-Saturns, with radii between 2.6 and 18 $R_oplus$, and equilibrium temperatures between 440 and 2000 K. In this paper we identify several targets of potential interest for future characterization studies, demonstrate the utility of transit follow-up observations for planet validation and ephemeris refinement, and present new imaging and spectroscopy data. Our simultaneous analysis of the K2 and Spitzer light curves yields improved estimates of the planet radii, and multi-wavelength information which help validate their planetary nature, including the previously un-validated candidate EPIC 205686202.01 (K2-289 b). Our Spitzer observations yield an order of magnitude increase in ephemeris precision, thus paving the way for efficient future study of these interesting systems by reducing the typical transit timing uncertainty in mid-2021 from several hours to a dozen or so minutes. K2-53 b, K2-289 b, K2-174 b, K2-87 b, and K2-90 b are promising radial velocity (RV) targets given the performance of spectrographs available today or in development, and the M3V star K2-124 hosts a temperate sub-Neptune that is potentially a good target for both RV and atmospheric characterization studies.
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