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Split learning for health: Distributed deep learning without sharing raw patient data

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 Added by Praneeth Vepakomma
 Publication date 2018
and research's language is English




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Can health entities collaboratively train deep learning models without sharing sensitive raw data? This paper proposes several configurations of a distributed deep learning method called SplitNN to facilitate such collaborations. SplitNN does not share raw data or model details with collaborating institutions. The proposed configurations of splitNN cater to practical settings of i) entities holding different modalities of patient data, ii) centralized and local health entities collaborating on multiple tasks and iii) learning without sharing labels. We compare performance and resource efficiency trade-offs of splitNN and other distributed deep learning methods like federated learning, large batch synchronous stochastic gradient descent and show highly encouraging results for splitNN.



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Electronic health records (EHR) systems contain vast amounts of medical information about patients. These data can be used to train machine learning models that can predict health status, as well as to help prevent future diseases or disabilities. However, getting patients medical data to obtain well-trained machine learning models is a challenging task. This is because sharing the patients medical records is prohibited by law in most countries due to patients privacy concerns. In this paper, we tackle this problem by sharing the models instead of the original sensitive data by using the mimic learning approach. The idea is first to train a model on the original sensitive data, called the teacher model. Then, using this model, we can transfer its knowledge to another model, called the student model, without the need to learn the original data used in training the teacher model. The student model is then shared to the public and can be used to make accurate predictions. To assess the mimic learning approach, we have evaluated our scheme using different medical datasets. The results indicate that the student model mimics the teacher model performance in terms of prediction accuracy without the need to access to the patients original data records.
562 - Yuqi Si , Jingcheng Du , Zhao Li 2020
Patient representation learning refers to learning a dense mathematical representation of a patient that encodes meaningful information from Electronic Health Records (EHRs). This is generally performed using advanced deep learning methods. This study presents a systematic review of this field and provides both qualitative and quantitative analyses from a methodological perspective. We identified studies developing patient representations from EHRs with deep learning methods from MEDLINE, EMBASE, Scopus, the Association for Computing Machinery (ACM) Digital Library, and Institute of Electrical and Electronics Engineers (IEEE) Xplore Digital Library. After screening 363 articles, 49 papers were included for a comprehensive data collection. We noticed a typical workflow starting with feeding raw data, applying deep learning models, and ending with clinical outcome predictions as evaluations of the learned representations. Specifically, learning representations from structured EHR data was dominant (37 out of 49 studies). Recurrent Neural Networks were widely applied as the deep learning architecture (LSTM: 13 studies, GRU: 11 studies). Disease prediction was the most common application and evaluation (31 studies). Benchmark datasets were mostly unavailable (28 studies) due to privacy concerns of EHR data, and code availability was assured in 20 studies. We show the importance and feasibility of learning comprehensive representations of patient EHR data through a systematic review. Advances in patient representation learning techniques will be essential for powering patient-level EHR analyses. Future work will still be devoted to leveraging the richness and potential of available EHR data. Knowledge distillation and advanced learning techniques will be exploited to assist the capability of learning patient representation further.
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