We investigate the role of intense vortical structures, similar to those in a turbulent flow, in enhancing collisions (and coalescences) which lead to the formation of large aggregates in particle-laden flows. By using a Burgers vortex model, we show, in particular, that vortex stretching significantly enhances sharp inhomogeneities in spatial particle densities, related to the rapid ejection of particles from intense vortices. Furthermore our work shows how such spatial clustering leads to an enhancement of collision rates and extreme statistics of collisional velocities. We also study the role of poly-disperse suspensions in this enhancement. Our work uncovers an important principle which, {if valid for realistic turbulent flows, may be a factor in} how small nuclei water droplets in warm clouds can aggregate to sizes large enough to trigger rain.