We construct a multiplicative spectral sequence converging to the symplectic cohomology ring of any affine variety $X$, with first page built out of topological invariants associated to strata of any fixed normal crossings compactification $(M,mathbf{D})$ of $X$. We exhibit a broad class of pairs $(M,mathbf{D})$ (characterized by the absence of relative holomorphic spheres or vanishing of certain relative GW invariants) for which the spectral sequence degenerates, and a broad subclass of pairs (similarly characterized) for which the ring structure on symplectic cohomology can also be described topologically. Sample applications include: (a) a complete topological description of the symplectic cohomology ring of the complement, in any projective $M$, of the union of sufficiently many generic ample divisors whose homology classes span a rank one subspace, (b) complete additive and partial multiplicative computations of degree zero symplectic cohomology rings of many log Calabi-Yau varieties, and (c) a proof in many cases that symplectic cohomology is finitely generated as a ring. A key technical ingredient in our results is a logarithmic version of the PSS morphism, introduced in our earlier work [GP1].
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