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A Hybrid Frequency-domain/Image-domain Deep Network for Magnetic Resonance Image Reconstruction

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 Added by Roberto Souza
 Publication date 2018
and research's language is English




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Decreasing magnetic resonance (MR) image acquisition times can potentially reduce procedural cost and make MR examinations more accessible. Compressed sensing (CS)-based image reconstruction methods, for example, decrease MR acquisition time by reconstructing high-quality images from data that were originally sampled at rates inferior to the Nyquist-Shannon sampling theorem. In this work we propose a hybrid architecture that works both in the k-space (or frequency-domain) and the image (or spatial) domains. Our network is composed of a complex-valued residual U-net in the k-space domain, an inverse Fast Fourier Transform (iFFT) operation, and a real-valued U-net in the image domain. Our experiments demonstrated, using MR raw k-space data, that the proposed hybrid approach can potentially improve CS reconstruction compared to deep-learning networks that operate only in the image domain. In this study we compare our method with four previously published deep neural networks and examine their ability to reconstruct images that are subsequently used to generate regional volume estimates. We evaluated undersampling ratios of 75% and 80%. Our technique was ranked second in the quantitative analysis, but qualitative analysis indicated that our reconstruction performed the best in hard to reconstruct regions, such as the cerebellum. All images reconstructed with our method were successfully post-processed, and showed good volumetry agreement compared with the fully sampled reconstruction measures.



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Purpose: To introduce a novel deep learning based approach for fast and high-quality dynamic multi-coil MR reconstruction by learning a complementary time-frequency domain network that exploits spatio-temporal correlations simultaneously from complementary domains. Theory and Methods: Dynamic parallel MR image reconstruction is formulated as a multi-variable minimisation problem, where the data is regularised in combined temporal Fourier and spatial (x-f) domain as well as in spatio-temporal image (x-t) domain. An iterative algorithm based on variable splitting technique is derived, which alternates among signal de-aliasing steps in x-f and x-t spaces, a closed-form point-wise data consistency step and a weighted coupling step. The iterative model is embedded into a deep recurrent neural network which learns to recover the image via exploiting spatio-temporal redundancies in complementary domains. Results: Experiments were performed on two datasets of highly undersampled multi-coil short-axis cardiac cine MRI scans. Results demonstrate that our proposed method outperforms the current state-of-the-art approaches both quantitatively and qualitatively. The proposed model can also generalise well to data acquired from a different scanner and data with pathologies that were not seen in the training set. Conclusion: The work shows the benefit of reconstructing dynamic parallel MRI in complementary time-frequency domains with deep neural networks. The method can effectively and robustly reconstruct high-quality images from highly undersampled dynamic multi-coil data ($16 times$ and $24 times$ yielding 15s and 10s scan times respectively) with fast reconstruction speed (2.8s). This could potentially facilitate achieving fast single-breath-hold clinical 2D cardiac cine imaging.
Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of diseases. Reconstruction algorithms entail transforming signals collected by acquisition hardware into interpretable images. Reconstruction is a challenging task given the ill-posed of the problem and the absence of exact analytic inverse transforms in practical cases. While the last decades witnessed impressive advancements in terms of new modalities, improved temporal and spatial resolution, reduced cost, and wider applicability, several improvements can still be envisioned such as reducing acquisition and reconstruction time to reduce patients exposure to radiation and discomfort while increasing clinics throughput and reconstruction accuracy. Furthermore, the deployment of biomedical imaging in handheld devices with small power requires a fine balance between accuracy and latency.
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