We prove dynamical dichotomy into scattering and blow-up (in a weak sense) for all radial solutions of the Zakharov system in the energy space of four spatial dimensions that have less energy than the ground state, which is written using the Aubin-Talenti function. The dichotomy is characterized by the critical mass of the wave component of the ground state. The result is similar to that by Kenig and Merle for the energy-critical nonlinear Schrodinger equation (NLS). Unlike NLS, however, the most difficult interaction in the proof stems from the free wave component. In order to control it, the main novel ingredient we develop in this paper is a uniform global Strichartz estimate for the linear Schrodinger equation with a potential of subcritical mass solving a wave equation. This estimate, as well as the proof, may be of independent interest. For the scattering proof, we follow the idea by Dodson and Murphy.