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Register a new userConditional Infilling GANs for Data Augmentation in Mammogram Classification
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Added by
Eric Wu
Publication date
2018
fields
Informatics Engineering
and research's language is
English
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Deep learning approaches to breast cancer detection in mammograms have recently shown promising results. However, such models are constrained by the limited size of publicly available mammography datasets, in large part due to privacy concerns and the high cost of generating expert annotations. Limited dataset size is further exacerbated by substantial class imbalance since normal images dramatically outnumber those with findings. Given the rapid progress of generative models in synthesizing realistic images, and the known effectiveness of simple data augmentation techniques (e.g. horizontal flipping), we ask if it is possible to synthetically augment mammogram datasets using generative adversarial networks (GANs). We train a class-conditional GAN to perform contextual in-filling, which we then use to synthesize lesions onto healthy screening mammograms. First, we show that GANs are capable of generating high-resolution synthetic mammogram patches. Next, we experimentally evaluate using the augmented dataset to improve breast cancer classification performance. We observe that a ResNet-50 classifier trained with GAN-augmented training data produces a higher AUROC compared to the same model trained only on traditionally augmented data, demonstrating the potential of our approach.
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Contemporary Artificial Intelligence technologies allow for the employment of Computer Vision to discern good crops from bad, providing a step in the pipeline of selecting healthy fruit from undesirable fruit, such as those which are mouldy or gangrenous. State-of-the-art works in the field report high accuracy results on small datasets (<1000 images), which are not representative of the population regarding real-world usage. The goals of this study are to further enable real-world usage by improving generalisation with data augmentation as well as to reduce overfitting and energy usage through model pruning. In this work, we suggest a machine learning pipeline that combines the ideas of fine-tuning, transfer learning, and generative model-based training data augmentation towards improving fruit quality image classification. A linear network topology search is performed to tune a VGG16 lemon quality classification model using a publicly-available dataset of 2690 images. We find that appending a 4096 neuron fully connected layer to the convolutional layers leads to an image classification accuracy of 83.77%. We then train a Conditional Generative Adversarial Network on the training data for 2000 epochs, and it learns to generate relatively realistic images. Grad-CAM analysis of the model trained on real photographs shows that the synthetic images can exhibit classifiable characteristics such as shape, mould, and gangrene. A higher image classification accuracy of 88.75% is then attained by augmenting the training with synthetic images, arguing that Conditional Generative Adversarial Networks have the ability to produce new data to alleviate issues of data scarcity. Finally, model pruning is performed via polynomial decay, where we find that the Conditional GAN-augmented classification network can retain 81.16% classification accuracy when compressed to 50% of its original size.
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