We show that the Nielsen-Ninomiya no-go theorem still holds on Floquet lattice: there is an equal number of right-handed and left-handed Weyl points in 3D Floquet lattice. However, in the adiabatic limit, where the time evolution of low-energy subspace is decoupled from the high-energy subspace, we show that the bulk dynamics in the low-energy subspace can be described by Floquet bands with purely left/right-handed Weyl points, despite the no-go theorem. For the adiabatic evolution of two bands, we show that the difference of the number of right-handed and left-handed Weyl points equals twice the winding number of the Floquet operator of the low-energy subspace over the Brillouin zone, thus guaranteeing the number of Weyl points to be even. Based on this observation, we propose to realize purely left/right-handed Weyl points in the adiabatic limit using a Hamiltonian obtained through dimensional reduction of four-dimensional quantum Hall system. We address the breakdown of the adiabatic limit on the surface due to the presence of gapless boundary states. This effect induces a circular motion of a wave packet in an applied magnetic field, travelling alternatively in the low-energy and high-energy subspace of the system.