A general analysis of possible violation of CP in processes like $tau to Kpi u$, for unpolarized $tau$ is presented. In this paper, we derive the new contributions to the effective Hamiltonian governs $vertDelta S vert=1$ semileptonic tau decays in the framework of two Higgs doublet model with generic Yukawa structure and Leptoquarks models. Within these models, we list all operators, in the effective Hamiltonian and provide analytical expression for their corresponding Wilson coefficients. Moreover, we analyze the role of the different contributions, originating from the scalar, vecor and tensor hadronic currents, in generating direct CP asymmetry in the decay rate of $tau^-to K^-pi^0 u_tau$. We show that non vanishing direct CP asymmetry in the decay rate of $tau^-to K^-pi^0 u_tau$ can be generated due to the presence of both, the weak phase in the Wilson coefficient corresponding to the tensor operator and the strong phase difference resulting from the interference between the form factors expressing the matrix elements of the vector and tensor hadronic currents. After taking into account all relevant constraints, we find that the generated direct CP asymmetry is of order $10^{-8}$ which is several orders of magnitude larger than the standard model prediction. We show also that, in two Higgs doublet model with generic Yukawa structure , direct local or non integrated CP violation can be as large as $0.3$ % not far from experimental possibilities. This kind of asymmetry can be generated due to the interference between vector and scalar contributions with different weak phases which is not the case in the SM.