There is an increased appreciation for, and utilization of, social networks to disseminate various kinds of interventions in a target population. Homophily, the tendency of people to be similar to those they interact with, can create within-group cohesion but at the same time can also lead to societal segregation. In public health, social segregation can form barriers to the spread of health interventions from one group to another. We analyzed the structure of social networks in 75 villages in Karnataka, India, both at the level of individuals and network communities. We found all villages to be strongly segregated at the community level, especially along the lines of caste and sex, whereas other socioeconomic variables, such as age and education, were only weakly associated with these groups in the network. While the studied networks are densely connected, our results indicate that the villages are highly segregated.