The Near-Infrared Spectrograph (NIRSpec) is one of four instruments aboard the James Webb Space Telescope (JWST). NIRSpec is developed by ESA with AIRBUS Defence & Space as prime contractor. The calibration of its various observing modes is a fundamental step to achieve the mission science goals and provide users with the best quality data from early on in the mission. Extensive testing of NIRSpec on the ground, aided by a detailed model of the instrument, allow us to derive initial corrections for the foreseeable calibrations. We present a snapshot of the current calibration scheme that will be revisited once JWST is in orbit.