We mainly study the M-estimation method for the high-dimensional linear regression model, and discuss the properties of M-estimator when the penalty term is the local linear approximation. In fact, M-estimation method is a framework, which covers the methods of the least absolute deviation, the quantile regression, least squares regression and Huber regression. We show that the proposed estimator possesses the good properties by applying certain assumptions. In the part of numerical simulation, we select the appropriate algorithm to show the good robustness of this method