Do you want to publish a course? Click here

A fully automated framework for lung tumour detection, segmentation and analysis

233   0   0.0 ( 0 )
 Added by Devesh Walawalkar
 Publication date 2018
and research's language is English




Ask ChatGPT about the research

Early and correct diagnosis is a very important aspect of cancer treatment. Detection of tumour in Computed Tomography scan is a tedious and tricky task which requires expert knowledge and a lot of human working hours. As small human error is present in any work he does, it is possible that a CT scan could be misdiagnosed causing the patient to become terminal. This paper introduces a novel fully automated framework which helps to detect and segment tumour, if present in a lung CT scan series. It also provides useful analysis of the detected tumour such as its approximate volume, centre location and more. The framework provides a single click solution which analyses all CT images of a single patient series in one go. It helps to reduce the work of manually going through each CT slice and provides quicker and more accurate tumour diagnosis. It makes use of customized image processing and image segmentation methods, to detect and segment the prospective tumour region from the CT scan. It then uses a trained ensemble classifier to correctly classify the segmented region as being tumour or not. Tumour analysis further computed can then be used to determine malignity of the tumour. With an accuracy of 98.14%, the implemented framework can be used in various practical scenarios, capable of eliminating need of any expert pathologist intervention.



rate research

Read More

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the different ILD pathologies in thoracic CT scans, yet their manifestation often appears similar. In this study, we propose the use of a deep purely convolutional neural network for the semantic segmentation of ILD patterns, as the basic component of a computer aided diagnosis (CAD) system for ILDs. The proposed CNN, which consists of convolutional layers with dilated filters, takes as input a lung CT image of arbitrary size and outputs the corresponding label map. We trained and tested the network on a dataset of 172 sparsely annotated CT scans, within a cross-validation scheme. The training was performed in an end-to-end and semi-supervised fashion, utilizing both labeled and non-labeled image regions. The experimental results show significant performance improvement with respect to the state of the art.
Early detection and segmentation of skin lesions is crucial for timely diagnosis and treatment, necessary to improve the survival rate of patients. However, manual delineation is time consuming and subject to intra- and inter-observer variations among dermatologists. This underlines the need for an accurate and automatic approach to skin lesion segmentation. To tackle this issue, we propose a multi-task convolutional neural network (CNN) based, joint detection and segmentation framework, designed to initially localize the lesion and subsequently, segment it. A `Faster region-based convolutional neural network (Faster-RCNN) which comprises a region proposal network (RPN), is used to generate bounding boxes/region proposals, for lesion localization in each image. The proposed regions are subsequently refined using a softmax classifier and a bounding-box regressor. The refined bounding boxes are finally cropped and segmented using `SkinNet, a modified version of U-Net. We trained and evaluated the performance of our network, using the ISBI 2017 challenge and the PH2 datasets, and compared it with the state-of-the-art, using the official test data released as part of the challenge for the former. Our approach outperformed others in terms of Dice coefficients ($>0.93$), Jaccard index ($>0.88$), accuracy ($>0.96$) and sensitivity ($>0.95$), across five-fold cross validation experiments.
Our previous works have demonstrated that visually realistic 3D meshes can be automatically reconstructed with low-cost, off-the-shelf unmanned aerial systems (UAS) equipped with capable cameras, and efficient photogrammetric software techniques. However, such generated data do not contain semantic information/features of objects (i.e., man-made objects, vegetation, ground, object materials, etc.) and cannot allow the sophisticated user-level and system-level interaction. Considering the use case of the data in creating realistic virtual environments for training and simulations (i.e., mission planning, rehearsal, threat detection, etc.), segmenting the data and extracting object information are essential tasks. Thus, the objective of this research is to design and develop a fully automated photogrammetric data segmentation and object information extraction framework. To validate the proposed framework, the segmented data and extracted features were used to create virtual environments in the authors previously designed simulation tool i.e., Aerial Terrain Line of Sight Analysis System (ATLAS). The results showed that 3D mesh trees could be replaced with geo-typical 3D tree models using the extracted individual tree locations. The extracted tree features (i.e., color, width, height) are valuable for selecting the appropriate tree species and enhance visual quality. Furthermore, the identified ground material information can be taken into consideration for pathfinding. The shortest path can be computed not only considering the physical distance, but also considering the off-road vehicle performance capabilities on different ground surface materials.
Purpose: Development of a fast and fully automated deep learning pipeline (FatSegNet) to accurately identify, segment, and quantify abdominal adipose tissue on Dixon MRI from the Rhineland Study - a large prospective population-based study. Method: FatSegNet is composed of three stages: (i) consistent localization of the abdominal region using two 2D-Competitive Dense Fully Convolutional Networks (CDFNet), (ii) segmentation of adipose tissue on three views by independent CDFNets, and (iii) view aggregation. FatSegNet is trained with 33 manually annotated subjects, and validated by: 1) comparison of segmentation accuracy against a testingset covering a wide range of body mass index (BMI), 2) test-retest reliability, and 3) robustness in a large cohort study. Results: The CDFNet demonstrates increased robustness compared to traditional deep learning networks. FatSegNet dice score outperforms manual raters on the abdominal visceral adipose tissue (VAT, 0.828 vs. 0.788), and produces comparable results on subcutaneous adipose tissue (SAT, 0.973 vs. 0.982). The pipeline has very small test-retest absolute percentage difference and excellent agreement between scan sessions (VAT: APD = 2.957%, ICC=0.998 and SAT: APD= 3.254%, ICC=0.996). Conclusion: FatSegNet can reliably analyze a 3D Dixon MRI in1 min. It generalizes well to different body shapes, sensitively replicates known VAT and SAT volume effects in a large cohort study, and permits localized analysis of fat compartments.
Due to medical data privacy regulations, it is often infeasible to collect and share patient data in a centralised data lake. This poses challenges for training machine learning algorithms, such as deep convolutional networks, which often require large numbers of diverse training examples. Federated learning sidesteps this difficulty by bringing code to the patient data owners and only sharing intermediate model training updates among them. Although a high-accuracy model could be achieved by appropriately aggregating these model updates, the model shared could indirectly leak the local training examples. In this paper, we investigate the feasibility of applying differential-privacy techniques to protect the patient data in a federated learning setup. We implement and evaluate practical federated learning systems for brain tumour segmentation on the BraTS dataset. The experimental results show that there is a trade-off between model performance and privacy protection costs.
comments
Fetching comments Fetching comments
Sign in to be able to follow your search criteria
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا