We present a number of notable results from the VLT-FLAMES Tarantula Survey (VFTS), an ESO Large Program during which we obtained multi-epoch medium-resolution optical spectroscopy of a very large sample of over 800 massive stars in the 30 Doradus region of the Large Magellanic Cloud (LMC). This unprecedented data-set has enabled us to address some key questions regarding atmospheres and winds, as well as the evolution of (very) massive stars. Here we focus on O-type runaways, the width of the main sequence, and the mass-loss rates for (very) massive stars. We also provide indications for the presence of a top-heavy initial mass function (IMF) in 30 Dor.