We study out-of-time order correlators (OTOCs) of the form $langlehat A(t)hat B(0)hat C(t)hat D(0)rangle$ for a quantum system weakly coupled to a dissipative environment. Such an open system may serve as a model of, e.g., a small region in a disordered interacting medium coupled to the rest of this medium considered as an environment. We demonstrate that for a system with discrete energy levels the OTOC saturates exponentially $propto sum a_i e^{-t/tau_i}+const$ to a constant value at $trightarrowinfty$, in contrast with quantum-chaotic systems which exhibit exponential growth of OTOCs. Focussing on the case of a two-level system, we calculate microscopically the decay times $tau_i$ and the value of the saturation constant. Because some OTOCs are immune to dephasing processes and some are not, such correlators may decay on two sets of parametrically different time scales related to inelastic transitions between the system levels and to pure dephasing processes, respectively. In the case of a classical environment, the evolution of the OTOC can be mapped onto the evolution of the density matrix of two systems coupled to the same dissipative environment.
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