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A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstruction

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 Added by Jo Schlemper
 Publication date 2017
and research's language is English




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Inspired by recent advances in deep learning, we propose a framework for reconstructing dynamic sequences of 2D cardiac magnetic resonance (MR) images from undersampled data using a deep cascade of convolutional neural networks (CNNs) to accelerate the data acquisition process. In particular, we address the case where data is acquired using aggressive Cartesian undersampling. Firstly, we show that when each 2D image frame is reconstructed independently, the proposed method outperforms state-of-the-art 2D compressed sensing approaches such as dictionary learning-based MR image reconstruction, in terms of reconstruction error and reconstruction speed. Secondly, when reconstructing the frames of the sequences jointly, we demonstrate that CNNs can learn spatio-temporal correlations efficiently by combining convolution and data sharing approaches. We show that the proposed method consistently outperforms state-of-the-art methods and is capable of preserving anatomical structure more faithfully up to 11-fold undersampling. Moreover, reconstruction is very fast: each complete dynamic sequence can be reconstructed in less than 10s and, for the 2D case, each image frame can be reconstructed in 23ms, enabling real-time applications.



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The acquisition of Magnetic Resonance Imaging (MRI) is inherently slow. Inspired by recent advances in deep learning, we propose a framework for reconstructing MR images from undersampled data using a deep cascade of convolutional neural networks to accelerate the data acquisition process. We show that for Cartesian undersampling of 2D cardiac MR images, the proposed method outperforms the state-of-the-art compressed sensing approaches, such as dictionary learning-based MRI (DLMRI) reconstruction, in terms of reconstruction error, perceptual quality and reconstruction speed for both 3-fold and 6-fold undersampling. Compared to DLMRI, the error produced by the method proposed is approximately twice as small, allowing to preserve anatomical structures more faithfully. Using our method, each image can be reconstructed in 23 ms, which is fast enough to enable real-time applications.
Accelerating the data acquisition of dynamic magnetic resonance imaging (MRI) leads to a challenging ill-posed inverse problem, which has received great interest from both the signal processing and machine learning community over the last decades. The key ingredient to the problem is how to exploit the temporal correlation of the MR sequence to resolve the aliasing artefact. Traditionally, such observation led to a formulation of a non-convex optimisation problem, which were solved using iterative algorithms. Recently, however, deep learning based-approaches have gained significant popularity due to its ability to solve general inversion problems. In this work, we propose a unique, novel convolutional recurrent neural network (CRNN) architecture which reconstructs high quality cardiac MR images from highly undersampled k-space data by jointly exploiting the dependencies of the temporal sequences as well as the iterative nature of the traditional optimisation algorithms. In particular, the proposed architecture embeds the structure of the traditional iterative algorithms, efficiently modelling the recurrence of the iterative reconstruction stages by using recurrent hidden connections over such iterations. In addition, spatiotemporal dependencies are simultaneously learnt by exploiting bidirectional recurrent hidden connections across time sequences. The proposed algorithm is able to learn both the temporal dependency and the iterative reconstruction process effectively with only a very small number of parameters, while outperforming current MR reconstruction methods in terms of computational complexity, reconstruction accuracy and speed.
Several variants of Convolutional Neural Networks (CNN) have been developed for Magnetic Resonance (MR) image reconstruction. Among them, U-Net has shown to be the baseline architecture for MR image reconstruction. However, sub-sampling is performed by its pooling layers, causing information loss which in turn leads to blur and missing fine details in the reconstructed image. We propose a modification to the U-Net architecture to recover fine structures. The proposed network is a wavelet packet transform based encoder-decoder CNN with residual learning called CNN. The proposed WCNN has discrete wavelet transform instead of pooling and inverse wavelet transform instead of unpooling layers and residual connections. We also propose a deep cascaded framework (DC-WCNN) which consists of cascades of WCNN and k-space data fidelity units to achieve high quality MR reconstruction. Experimental results show that WCNN and DC-WCNN give promising results in terms of evaluation metrics and better recovery of fine details as compared to other methods.
Undersampling the k-space data is widely adopted for acceleration of Magnetic Resonance Imaging (MRI). Current deep learning based approaches for supervised learning of MRI image reconstruction employ real-valued operations and representations by treating complex valued k-space/spatial-space as real values. In this paper, we propose complex dense fully convolutional neural network ($mathbb{C}$DFNet) for learning to de-alias the reconstruction artifacts within undersampled MRI images. We fashioned a densely-connected fully convolutional block tailored for complex-valued inputs by introducing dedicated layers such as complex convolution, batch normalization, non-linearities etc. $mathbb{C}$DFNet leverages the inherently complex-valued nature of input k-space and learns richer representations. We demonstrate improved perceptual quality and recovery of anatomical structures through $mathbb{C}$DFNet in contrast to its real-valued counterparts.
Demosaicking and denoising are among the most crucial steps of modern digital camera pipelines and their joint treatment is a highly ill-posed inverse problem where at-least two-thirds of the information are missing and the rest are corrupted by noise. This poses a great challenge in obtaining meaningful reconstructions and a special care for the efficient treatment of the problem is required. While there are several machine learning approaches that have been recently introduced to deal with joint image demosaicking-denoising, in this work we propose a novel deep learning architecture which is inspired by powerful classical image regularization methods and large-scale convex optimization techniques. Consequently, our derived network is more transparent and has a clear interpretation compared to alternative competitive deep learning approaches. Our extensive experiments demonstrate that our network outperforms any previous approaches on both noisy and noise-free data. This improvement in reconstruction quality is attributed to the principled way we design our network architecture, which also requires fewer trainable parameters than the current state-of-the-art deep network solution. Finally, we show that our network has the ability to generalize well even when it is trained on small datasets, while keeping the overall number of trainable parameters low.
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