We present a multi-wavelength photometric catalog in the COSMOS field as part of the observations by the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS). The catalog is based on Hubble Space Telescope Wide Field Camera 3 (HST/WFC3) and Advanced Camera for Surveys (ACS) observations of the COSMOS field (centered at RA: $10^h00^m28^s$, Dec:$+02^{circ}12^{prime}21^{primeprime}$). The final catalog has 38671 sources with photometric data in forty two bands from UV to the infrared ($rm sim 0.3-8,mu m$). This includes broad-band photometry from the HST, CFHT, Subaru, VISTA and Spitzer Space Telescope in the visible, near infrared and infrared bands along with intermediate and narrow-band photometry from Subaru and medium band data from Mayall NEWFIRM. Source detection was conducted in the WFC3 F160W band (at $rm 1.6,mu m$) and photometry is generated using the Template FITting algorithm. We further present a catalog of the physical properties of sources as identified in the HST F160W band and measured from the multi-band photometry by fitting the observed spectral energy distributions of sources against templates.