We have monitored the Cassiopeia dwarf galaxy (IC 10) in a series of 10 Chandra ACIS-S observations to capture its variable and transient X-ray source population, which is expected to be dominated by High Mass X-ray Binaries (HMXBs). We present a sample of 21 X-ray sources that are variable between observations at the 3 sigma level, from a catalog of 110 unique point sources. We find 4 transients (flux variability ratio greater than 10) and a further 8 objects with ratio > 5. The observations span years 2003 - 2010 and reach a limiting luminosity of >10$^{35}$ erg/s, providing sensitivity to X-ray binaries in IC 10 as well as flare stars in the foreground Milky Way. The nature of the variable sources is investigated from light-curves, X-ray spectra, energy quantiles, and optical counterparts. The purpose of this study is to discover the composition of the X-ray binary population in a young starburst environment. IC 10 provides a sharp contrast in stellar population age (<10 My) when compared to the Magellanic Clouds (40-200 My) where most of the known HMXBs reside. We find 10 strong HMXB candidates, 2 probable background Active Galactic Nuclei, 4 foreground flare-stars or active binaries, and 5 not yet classifiable sources. Complete classification of the sample requires optical spectroscopy for radial velocity analysis and deeper X-ray observations to obtain higher S/N spectra and search for pulsations. A catalog and supporting dataset are provided.
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