To evaluate a fitting of a statistical model to given data, calculating a conditional $p$ value by a Markov chain Monte Carlo method is one of the effective approaches. For this purpose, a Markov basis plays an important role because it guarantees the connectivity of the chain for unbiasedness of the estimation, and therefore is investigated in various settings such as incomplete tables or subtable sum constraints. In this paper, we consider the two-way change-point model for the ladder determinantal table, which is an extension of these two previous works. Our main result is based on the theory of Groebner basis for the distributive lattice. We give a numerical example for actual data.