Let $F$ be a connected graph with $ell$ vertices. The existence of a subgraph isomorphic to $F$ can be defined in first-order logic with quantifier depth no better than $ell$, simply because no first-order formula of smaller quantifier depth can distinguish between the complete graphs $K_ell$ and $K_{ell-1}$. We show that, for some $F$, the existence of an $F$ subgraph in emph{sufficiently large} connected graphs is definable with quantifier depth $ell-3$. On the other hand, this is never possible with quantifier depth better than $ell/2$. If we, however, consider definitions over connected graphs with sufficiently large treewidth, the quantifier depth can for some $F$ be arbitrarily small comparing to $ell$ but never smaller than the treewidth of $F$. Moreover, the definitions over highly connected graphs require quantifier depth strictly more than the density of $F$. Finally, we determine the exact values of these descriptive complexity parameters for all connected pattern graphs $F$ on 4 vertices.
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