We report on a comprehensive all-sky search for periodic gravitational waves in the frequency band 100-1500 Hz and with a frequency time derivative in the range of $[-1.18, +1.00]times 10^{-8}$ Hz/s. Such a signal could be produced by a nearby spinning and slightly non-axisymmetric isolated neutron star in our galaxy. This search uses the data from the Initial LIGO sixth science run and covers a larger parameter space with respect to any past search. A Loosely Coherent detection pipeline was applied to follow up weak outliers in both Gaussian (95% recovery rate) and non-Gaussian (75% recovery rate) bands. No gravitational wave signals were observed, and upper limits were placed on their strength. Our smallest upper limit on worst-case (linearly polarized) strain amplitude $h_0$ is ${9.7}times 10^{-25}$ near 169 Hz, while at the high end of our frequency range we achieve a worst-case upper limit of ${5.5}times 10^{-24}$. Both cases refer to all sky locations and entire range of frequency derivative values.
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