This is the first of a series of papers presenting the Modules for Experiments in Stellar Astrophysics (MESA) Isochrones and Stellar Tracks (MIST) project, a new comprehensive set of stellar evolutionary tracks and isochrones computed using MESA, a state-of-the-art open-source 1D stellar evolution package. In this work, we present models with solar-scaled abundance ratios covering a wide range of ages ($5 leq rm log(Age);[yr] leq 10.3$), masses ($0.1 leq M/M_{odot} leq 300$), and metallicities ($-2.0 leq rm [Z/H] leq 0.5$). The models are self-consistently and continuously evolved from the pre-main sequence to the end of hydrogen burning, the white dwarf cooling sequence, or the end of carbon burning, depending on the initial mass. We also provide a grid of models evolved from the pre-main sequence to the end of core helium burning for $-4.0 leq rm [Z/H] < -2.0$. We showcase extensive comparisons with observational constraints as well as with some of the most widely used existing models in the literature. The evolutionary tracks and isochrones can be downloaded from the project website at http://waps.cfa.harvard.edu/MIST/.
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