We calculate the yield of lepton pair production from jet-plasma interaction where the plasma is anisotropic in momentum space. We compare both the $M$ and $p_T$ distributions from such process with the Drell-Yan contribution. It is observed that the invariant mass distribution of lepton pair from such process dominate over the Drell-Yan up to $3$ GeV at RHIC and up to $10$ GeV at LHC. Moreover, it is found that the contribution from anistropic quark gluon plasma (AQGP) increases marginally compared to the isotropic QGP. In case of $p_T$-distribution we observe an increase by a factor of $3-4$ in the entire $p_T$-range at RHIC for AQGP. However, at LHC the change in the $p_T$-distribution is marginal as compared to the isotropic case.