The quark-line disconnected diagram is a potentially important ingredient in lattice QCD calculations of the hadronic vacuum polarization contribution to the anomalous magnetic moment of the muon. It is also a notoriously difficult one to evaluate. Here, for the first time, we give an estimate of this contribution based on lattice QCD results that have a statistically significant signal, albeit at one value of the lattice spacing and an unphysically heavy value of the $u/d$ quark mass. We use HPQCDs method of determining the anomalous magnetic moment by reconstructing the Adler function from time-moments of the current-current correlator at zero spatial momentum. Our results lead to a total (including $u$, $d$ and $s$ quarks) quark-line disconnected contribution to $a_{mu}$ of $-0.15%$ of the $u/d$ hadronic vacuum polarization contribution with an uncertainty which is 1% of that contribution.