In this article we prove existence of the asymptotic entropy for isotropic random walks on regular Fuchsian buildings. Moreover, we give formulae for the asymptotic entropy, and prove that it is equal to the rate of escape of the random walk with respect to the Green distance. When the building arises from a Fuchsian Kac-Moody group our results imply results for random walks induced by bi-invariant measures on these groups, however our results are proven in the general setting without the assumption of any group acting on the building. The main idea is to consider the retraction of the isotropic random walk onto an apartment of the building, to prove existence of the asymptotic entropy for this retracted walk, and to `lift this in order to deduce the existence of the entropy for the random walk on the building.