Antiprotons are regarded as a powerful probe for Dark Matter (DM) indirect detection and indeed current data from PAMELA have been shown to lead to stringent constraints. However, in order to exploit their constraining/discovery power properly, great attention must be put into effects (linked to their propagation in the Galaxy) which may be perceived as subleading but actually prove to be quite relevant. We revisit the computation of the astrophysical background and of the DM antiproton fluxes fully including the effects of: diffusive reacceleration, energy losses including tertiary component and solar modulation (in a force field approximation). Using the updated proton and helium fluxes just released by the AMS experiment we reevaluate the secondary astrophysical antiproton to proton ratio and its uncertainties, and compare it with the ratio preliminarly reported by AMS. We find no unambiguous evidence for a significant excess with respect to expectations. Yet, some preference for a flatter energy dependence of the diffusion coefficient (with respect to the {sc Med} benchmark often used in the literature) starts to emerge. Finally, we provide a first assessment of the room left for exotic components such as Galactic Dark Matter annihilation, deriving new stringent constraints.