We compute the hadronic production of top-antitop pairs in association with a Higgs boson at next-to-leading-order QCD, including the decay of the top and antitop quark into bottom quarks and leptons. Our computation is based on full leading and next-to-leading-order matrix elements for $e^+ u_e mu^-bar{ u}_mu b bar{b} H(j)$ and includes all non-resonant contributions, off-shell effects and interferences. Numerical results for the integrated cross section and several differential distributions are given for the LHC operating at 13 TeV using a fixed and a dynamical factorization and renormalization scale. The use of the dynamical instead of the fixed scale improves the perturbative stability in high-energy tails of most distributions, while the integrated cross section is hardly affected differing by only about one per cent and leading to the same K factor of 1.17.
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