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Register a new userHelium-3 and Helium-4 acceleration by high power laser pulses for hadron therapy
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The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions. This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (Magnetic Vortex Acceleration and hole-boring Radiation Pressure Acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He3 ions, having almost the same penetration depth as He4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.
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Dimensional effects in particle-in-cell (PIC) simulation of target normal sheath acceleration (TNSA) of protons are considered. As the spatial divergence of the laser-accelerated hot sheath electrons and the resulting space-charge electric field on the target backside depend on the spatial dimension, the maximum energy of the accelerated protons obtained from three-dimensional (3D) simulations is usually much less that from two-dimensional (2D) simulations. By closely examining the TNSA of protons in 2D and 3D PIC simulations, we deduce an empirical ratio between the maximum proton energies obtained from the 2D and 3D simulations. This ratio may be useful for estimating the maximum proton energy in realistic (3D) TNSA from the results of the corresponding 2D simulation. It is also shown that the scaling law also applies to TNSA from structured targets.
The future applications of the short-duration, multi-MeV ion beams produced in the interaction of high-intensity laser pulses with solid targets will require improvements in the conversion efficiency, peak ion energy, beam monochromaticity, and collimation. Regimes based on Radiation Pressure Acceleration (RPA) might be the dominant ones at ultrahigh intensities and be most suitable for specific applications. This regime may be reached already with present-day intensities using circularly polarized (CP) pulses thanks to the suppression of fast electron generation, so that RPA dominates over sheath acceleration at any intensity. We present a brief review of previous work on RPA with CP pulses and a few recent results. Parametric studies in one dimension were performed to identify the optimal thickness of foil targets for RPA and to study the effect of a short-scalelength preplasma. Three-dimensional simulations showed the importance of ``flat-top radial intensity profiles to minimise the rarefaction of thin targets and to address the issue of angular momentum conservation and absorption.
The characteristics of a MeV ion source driven by superintense, ultrashort laser pulses with circular polarization are studied by means of particle-in-cell simulations. Predicted features include high efficiency, large ion density, low divergence and the possibility of femtosecond duration. A comparison with the case of linearly polarized pulses is made.
In a laser plasma accelerator (LPA), a short and intense laser pulse propagating in a plasma drives a wakefield (a plasma wave with a relativistic phase velocity) that can sustain extremely large electric fields, enabling compact accelerating structures. Potential LPA applications include compact radiation sources and high energy linear colliders. We propose and study plasma wave excitation by an incoherent combination of a large number of low energy laser pulses (i.e., without constraining the pulse phases). We show that, in spite of the incoherent nature of electromagnetic fields within the volume occupied by the pulses, the excited wakefield is regular and its amplitude is comparable or equal to that obtained using a single, coherent pulse with the same energy. These results provide a path to the next generation of LPA-based applications, where incoherently combined multiple pulses may enable high repetition rate, high average power LPAs.
We investigate the target normal sheath acceleration of protons in thin aluminum targets irradiated at relativistic intensity by two time-separated ultrashort (35 fs) laser pulses. For identical laser pulses and target thicknesses of 3 and 6 $mu$m, we observe experimentally that the second pulse boosts the maximum energy and charge of the proton beam produced by the first pulse for time delays below $sim0.6-1$ ps. By using two-dimensional particle-in-cell simulations we examine the variation of the proton energy spectra with respect to the time-delay between the two pulses. We demonstrate that the expansion of the target front surface caused by the first pulse significantly enhances the hot-electron generation by the second pulse arriving after a few hundreds of fs time delay. This enhancement, however, does not suffice to further accelerate the fastest protons driven by the first pulse once three-dimensional quenching effects have set in. This implies a limit to the maximum time delay that leads to proton energy enhancement, which we theoretically determine.
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