John St. Bell was a physicist working most of his time at CERN and contributing intensively and sustainably to the development of Particle Physics and Collider Physics. As a hobby he worked on so-called foundations of quantum theory, that was that time very unpopular, even considered to be scientifically taboo. His 1964-theorem, showing that predictions of local realistic theories are different to those of quantum theory, initiated a new field in quantum physics: quantum information theory. The violation of Bells theorem, for instance, is a necessary and sufficient criterion for generating a secure key for cryptography at two distant locations. This contribution shows how Bells theorem can be brought to the realm of high energy physics and presents the first conclusive experimental feasible test for weakly decaying neutral mesons on the market. Strong experimental and theoretical limitations make a Bell test in weakly decaying systems such as mesons and hyperons very challenging, however, these systems show an unexpected and puzzling relation to another big open question: why is our Universe dominated by matter, why did the antimatter slip off the map? This long outstanding problem becomes a new perspective via the very idea behind quantum information.