Relativistic Invariance might be modified by Quantum Gravity effects. The interesting point which emerged in the last fifteen years is that remnants of possible Lorentz Invariance Violations could be present at energies much lower than their natural scale, and possibly affect Ultra High Energy Cosmic Rays phenomena. We discuss their status in the view of recent data from the Pierre Auger Observatory.
The assumption of Lorentz invariance is one of the founding principles of Modern Physics and violation of it would have profound implications to our understanding of the universe. For instance, certain theories attempting a unified theory of quantum gravity predict there could be an effective refractive index of the vacuum; the introduction of an energy dependent dispersion to photons could in turn lead to an observable Lorentz invariance violation signature. Whilst a very small effect on local scales the effect will be cumulative, and so for very high energy particles that travel very large distances the difference in arrival times could become sufficiently large to be detectable. This proceedings will look at testing for such Lorentz invariance violation (LIV) signatures in the astronomical lightcurves of gamma-ray emitting objects, with particular notice being given to the prospects for LIV testing with, the next generation observatory, the Cherenkov Telescope Array.
There has been much interest in possible violations of Lorentz invariance, particularly motivated by quantum gravity theories. It has been suggested that a small amount of Lorentz invariance violation (LIV) could turn off photomeson interactions of ultrahigh energy cosmic rays (UHECRs) with photons of the cosmic background radiation and thereby eliminate the resulting sharp steepening in the spectrum of the highest energy CRs predicted by Greisen Zatsepin and Kuzmin (GZK). Recent measurements of the UHECR spectrum reported by the HiRes and Auger collaborations, however, indicate the presence of the GZK effect. We present the results of a detailed calculation of the modification of the UHECR spectrum caused by LIV using the formalism of Coleman and Glashow. We then compare these results with the experimental UHECR data from Auger and HiRes. Based on these data, we find a best fit amount of LIV of $4.5^{+1.5}_{-4.5} times 10^{-23}$,consistent with an upper limit of $6 times 10^{-23}$. This possible amount of LIV can lead to a recovery of the cosmic ray spectrum at higher energies than presently observed. Such an LIV recovery effect can be tested observationally using future detectors.
I have shown that if we assume that the Standard Model of particle physics and Feynman-Weinberg quantum gravity holds at all times, then in the very early universe, the Cosmic Background Radiation (CBR) cannot couple to right handed electrons and quarks. If this property of CBR has persisted to the present day, the Ultra HIgh Energy Cosmic Rays (UHECR) can propagate a factor of ten further than they could if the CBR were an electromagnetic field, since most of the cross section for pion production when a UHECR hits a CBR photon is due to a quark spin flip, and such a flip cannot occur if the CBR photon cannot couple to right handed quarks. The GZM effect will still reduce the number of UHECR, but UHECR can arrive from a distance of a redshift of up to $z=0.1$. I show that taking this additional propagation distance into account allows us to identify the sources of 4 of the 6 UHECR which the Pierre Auger Collaboration could not identify, and also identify the source of the 320 EeV UHECR seen by the Flys Eye instrument. I suggest an experiment to test this hypothesis about the CBR.
Recently, molecular fingerprints extracted from three-dimensional (3D) structures using advanced mathematics, such as algebraic topology, differential geometry, and graph theory have been paired with efficient machine learning, especially deep learning algorithms to outperform other methods in drug discovery applications and competitions. This raises the question of whether classical 2D fingerprints are still valuable in computer-aided drug discovery. This work considers 23 datasets associated with four typical problems, namely protein-ligand binding, toxicity, solubility and partition coefficient to assess the performance of eight 2D fingerprints. Advanced machine learning algorithms including random forest, gradient boosted decision tree, single-task deep neural network and multitask deep neural network are employed to construct efficient 2D-fingerprint based models. Additionally, appropriate consensus models are built to further enhance the performance of 2D-fingerprintbased methods. It is demonstrated that 2D-fingerprint-based models perform as well as the state-of-the-art 3D structure-based models for the predictions of toxicity, solubility, partition coefficient and protein-ligand binding affinity based on only ligand information. However, 3D structure-based models outperform 2D fingerprint-based methods in complex-based protein-ligand binding affinity predictions.
Roberto Aloisio
,Denise Boncioli
,Armando di Matteo
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(2014)
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"Are Cosmic Rays still a valuable probe of Lorentz Invariance Violations in the Auger era?"
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Aurelio Grillo
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