As part of the Snowmass process, the Cosmic Frontier Indirect-Detection subgroup (CF2) has drawn on input from the Cosmic Frontier and the broader Particle Physics community to produce this document. The purposes of this report are to identify opportunities for dark matter science through indirect detection, to give an overview of the primary scientific drivers for indirect searches for dark matter, and to survey current and planned experiments that have, as a large part of their scientific program, the goal of searching for indirect (or astrophysical) signatures of dark matter. We primarily address existing experiments with a large U.S. role, or future experiments where a U.S. contribution is sought. We also address the limitations of this technique, and answer the tough questions relevant to this subgroup posed by the HEP community through the Snowmass process.