We present the various science cases for building Band 1 receivers as part of ALMAs ongoing Development Program. We describe the new frequency range for Band 1 of 35-52 GHz, a range chosen to maximize the receiver suites scientific impact. We first describe two key science drivers: 1) the evolution of grains in protoplanetary disks and debris disks, and 2) molecular gas in galaxies during the era of re-ionization. Studies of these topics with Band 1 receivers will significantly expand ALMAs Level 1 Science Goals. In addition, we describe a host of other exciting continuum and line science cases that require ALMAs high sensitivity and angular resolution. For example, ALMA Band 1 continuum data will probe the Sunyaev-Zeldovich Effect in galaxy clusters, Very Small Grains and spinning dust, ionized jets from young stars, spatial and flaring studies of Sgr A*, the acceleration sites of solar flares, pulsar wind nebulae, radio supernovae, and X-ray binaries. Furthermore, ALMA Band 1 line data will probe chemical differentiation in cloud cores, complex carbon chain molecules, extragalactic radio recombination lines, masers, magnetic fields through Zeeman effect measurements, molecular outflows from young stars, the co-evolution of star formation and active galactic nuclei, and the molecular content of galaxies at z ~ 3. ALMA provides similar to better sensitivities than the JVLA over 35-50 GHz, with differences increasing with frequency. ALMAs smaller antennas and shorter baselines, greater number of baselines, and single-dish capabilities, however, give it a significant edge for observing extended emission, making wide-field maps (mosaics), or attaining high image fidelity, as required by the described science cases.