This presentation describes a measurement of the neutrino mixing parameter, sin^2(2theta_13), from the Daya Bay Reactor Neutrino Experiment. Disappearance of electron antineutrinos at a distance of ~2 km from a set of six reactors, where the reactor flux is constrained by near detectors, has been clearly observed. The result, based on the ratio of observed to expected rate of antineutrinos, using 139 days of data taken between December 24, 2011 and May 11, 2012, is sin^2(2theta_13) = 0.089 +/- 0.010(stat.) +/- 0.005(syst.). Improvements in sensitivity from inclusion of additional data, spectral analysis, and improved calibration are expected in the future.