The astrophysical S-factor of the 4He-12C radiative capture is calculated in the potential model at the energy range 0.1-2.0 MeV. Radiative capture 12C(alpha,gamma)16O is extremely relevant for the fate of massive stars and determines if the remnant of a supernova explosion becomes a black hole or a neutron star. Because this reaction occurs at low-energies the experimental measurements is very difficult and perhaps impossible. In this paper, radiative capture of the 12C(alpha,gamma)16O reaction at very low-energies is taken as a case study. In comparison with other theoretical methods and available experimental data, excellent agreement is achieved for the astrophysical S-factor of this process.