The first three years of the LHC experiments at CERN have ended with the nightmare scenario: all tests, confirm the Standard Model of Particles so well that theorists must search for new physics without any experimental guidance. The supersymmetric theories, a privileged candidate for new physics are nearly excluded. As a potential escape from the crisis, we propose thinking about a series of astonishing relations suggesting fundamental interconnections between the quantum world and the large scale Universe. It seems reasonable that, for instance, the equation relating a quark-antiquark pair with the fundamental physical constants and cosmological parameters must be a sign of new physics. One of the intriguing possibilities is interpreting our relations as a signature of the quantum vacuum containing the virtual gravitational dipoles.