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Double di ffential fragmentation cross sections measurements of 95 MeV/u 12C on thin targets for hadrontherapy

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 Added by Sandrine Guesnon
 Publication date 2013
  fields Physics
and research's language is English




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During therapeutic treatment with heavy ions like carbon, the beam undergoes nuclear fragmentation and secondary light charged particles, in particular protons and alpha particles, are produced. To estimate the dose deposited into the tumors and the surrounding healthy tissues, an accurate prediction on the fluences of these secondary fragments is necessary. Nowadays, a very limited set of double di ffential carbon fragmentation cross sections are being measured in the energy range used in hadrontherapy (40 to 400 MeV/u). Therefore, new measurements are performed to determine the double di ffential cross section of carbon on di erent thin targets. This work describes the experimental results of an experiment performed on May 2011 at GANIL. The double di ffential cross sections and the angular distributions of secondary fragments produced in the 12C fragmentation at 95 MeV/u on thin targets (C, CH2, Al, Al2O3, Ti and PMMA) have been measured. The experimental setup will be precisely described, the systematic error study will be explained and all the experimental data will be presented.



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During therapeutic treatments using ions such as carbon, nuclear interactions between the incident ions and nuclei present in organic tissues may occur, leading to the attenuation of the incident beam intensity and to the production of secondary light charged particles. As the biological dose deposited in the tumor and the surrounding healthy tissues depends on the beam composition, an accurate knowledge of the fragmentation processes is thus essential. In particular, the nuclear interaction models have to be validated using experimental double differential cross sections which are still very scarce. An experiment was realized in 2011 at GANIL to obtain these cross sections for a 95 MeV/nucleon carbon beam on different thin targets for angles raging from 4 to 43{deg} . In order to complete these data, a new experiment was performed on September 2013 at GANIL to measure the fragmentation cross section at zero degree for a 95 MeV/nucleon carbon beam on thin targets. In this work, the experimental setup will be described, the analysis method detailed and the results presented.
122 - J. Dudouet 2013
During therapeutic treatment with heavier ions like carbon, the beam undergoes nuclear fragmentation and secondary light charged particles, in particular protons and alpha particles, are produced. To estimate the dose deposited into the tumors and the surrounding healthy tissues, the accuracy must be higher than ($pm$3% and$pm$1 mm). Therefore, measurements are performed to determine the double differential cross section for different reactions. In this paper, the analysis of data from 12C +12C reactions at 95 MeV/u are presented. The emitted particles are detected with DeltaEthin-DeltaEthick-E telescopes made of a stack of two silicon detectors and a CsI crystal. Two different methods are used to identify the particles. One is based on graphical cuts onto the DeltaE-E maps, the second is based on the so-called KaliVeda method using a functional description of DeltaE versus E. The results of the two methods will be presented in this paper as well as the comparison between both.
To get the energy spectrum distribution and cross-sections of emitted light charged particles and explore the nuclear reaction, a experiment of 80.5 MeV/u 12C beam bombarding on C, W, Cu, Au, Pb targets has been carried out at Institute of Modern Physics, Chinese Academy of Science. 30, 60 and 120 degree relative to the incident beam have been detected using three sets of telescope detectors. The results indicate that there is a tendency that heavier targets have larger double differential cross-sections and the emitted fragments are more likely to go forward. Besides, the decrease of cross-sections of fragments producing with the increasing emitted angles may follow some kind of pattern.
Dissipative 12C+12C reactions at 95 MeV are fully detected in charge with the GARFIELD and RCo apparatuses at LNL. A comparison to a dedicated Hauser-Feshbach calculation allows to select events which correspond, to a large extent, to the statistical evaporation of highly excited 24Mg, as well as to extract information on the isotopic distribution of the evaporation residues in coincidence with their complete evaporation chain. Residual deviations from a statistical behaviour are observed in alpha yields and attributed to the persistence of cluster correlations well above the 24Mg threshold for 6 alphas decay.
64 - T.Toshito , K.Kodama , L.Sihver 2007
We have studied charged nuclear fragments produced by 200 - 400 MeV/nucleon carbon ions, interacting with water and polycarbonate, using a newly developed emulsion detector. Total and partial charge-changing cross sections for the production of B, Be, and Li fragments were measured and compared with both previously published measurements, and model predictions. This study is of importance for validating and improving carbon ion therapy treatment planning systems, and for estimating the radiological risks for personnel on space missions, since carbon is a significant component of the Galactic Cosmic Rays.
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