KdV6 equation can be described as the Kupershmidt deformation of the KdV equation (see 2008, Phys. Lett. A 372: 263). In this paper, starting from the bi-Hamiltonian structure of the discrete integrable system, we propose a generalized Kupershmidt deformation to construct new discrete integrable systems. Toda hierarchy, Kac-van Moerbeke hierarchy and Ablowitz-Ladik hierarchy are considered. The Lax representations for these new deformed systems are presented. The generalized Kupershmidt deformation for the discrete integrable systems provides a new way to construct new discrete integrable systems.