A new method for the localization of the regions where small scale turbulent fluctuations are present in hypersonic flows is applied to the large-eddy simulation (LES) of a compressible turbulent jet with an initial Mach number equal to 5. The localization method used is called selective LES and is based on the exploitation of a scalar probe function $f$ which represents the magnitude of the stretching-tilting term of the vorticity equation normalized with the enstrophy (Tordella et al. 2007). For a fully developed turbulent field of fluctuations, statistical analysis shows that the probability that $f$ is larger than 2 is almost zero, and, for any given threshold, it is larger if the flow is under-resolved. By computing the spatial field of $f$ in each instantaneous realization of the simulation it is possible to locate the regions where the magnitude of the normalized vortical stretching-tilting is anomalously high. The sub-grid model is then introduced into the governing equations in such regions only. The results of the selective LES simulation are compared with those of a standard LES, where the sub-grid terms are used in the whole domain, and with those of a standard Euler simulation with the same resolution. The comparison is carried out by assuming as reference field a higher resolution Euler simulation of the same jet. It is shown that the selective LES modifies the dynamic properties of the flow to a lesser extent with respect to the classical LES. In particular, the prediction of the enstrophy, mean velocity and density distributions and of the energy and density spectra are substantially improved.